ManuScript Details
|
Paper Id:
|
IJARW1315
|
|
Title:
|
SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC
|
| Published in: |
International Journal Of All Research Writings |
| Publisher: |
IJARW |
| ISSN: |
2582-1008 |
| Volume / Issue: |
Volume 2 Issue 1 |
| Pages: |
6
|
| Published On: |
7/4/2020 4:01:48 AM (MM/dd/yyyy) |
Main Author Details
|
Name:
|
Mr.Bharat Dadhich |
| Institute: |
MAHATMA GANDHI COLLEGE OF PHARMACEUTICAL SCIENCES, Jaipur, Rajasthan |
Co - Author Details
| Author Name |
Author Institute |
| Dr. Dilip Agarwal |
MAHATMA GANDHI COLLEGE OF PHARMACEUTICAL SCIENCES, Jaipur, Rajasthan |
| Mr.Rakesh Goyal |
MAHATMA GANDHI COLLEGE OF PHARMACEUTICAL SCIENCES, Jaipur, Rajasthan |
Abstract
|
Research Area:
|
Pharmacy, Pharmacology & theraputics |
| KeyWord: |
Helicobacter pylori, HPLC, drug analysis, chromatography, gastrointestinal diseases |
| Abstract: |
Present investigation dealt with the developing of a reversed phase-high performance liquid chromatographic method for determination of tinidazole, clarithromycin and lansoprazole in pure state and ias a mixture. Chromatographic separation was performed isocratically on a LiChrospher® 100 RP-18 column. The flow rate was 1.0 ml/min and the detector was set at 280 nm. The method was developed at ambient temperature with a mobile phase, 40:60 v/v acetonitrile and phosphate buffer (0.001 M, pH 7.6). The selected conditions were applicable for separating tinidazole, clarithromycin and lansoprazole with retention times 5.37, 11.71 and 17.67 min, respectively. The method was validated for parameters including linearity, selectivity, precision and accuracy, limit of detection and limit of quantitation. Linear calibration curves were obtained in the concentration range of 125-1000.0, 5.0-40.0 and 7.5-60.0 μg/ml for tinidazole, clarithromycin and lansoprazole, respectively. The proposed method was found to be effective and could be used for quantification of these drugs in routine quality control practice. |
Citations
Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.
|
IEEE
|
Mr.Bharat Dadhich , Dr. Dilip Agarwal, Mr.Rakesh Goyal, "SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC", International Journal Of All Research Writings,
vol. 2, no. 1, pp. 9-14, 2020.
|
|
MLA
|
Mr.Bharat Dadhich , Dr. Dilip Agarwal, Mr.Rakesh Goyal "SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC." International Journal Of All Research Writings,
vol 2, no. 1, 2020, pp. 9-14.
|
|
APA
|
Mr.Bharat Dadhich , Dr. Dilip Agarwal, Mr.Rakesh Goyal (2020). SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC. International Journal Of All Research Writings,
2(1), 9-14.
|
SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC
Number Of Downloads - 41
Last downloaded on 03/07/2022
SIMULTANEOUS DETERMINATION TINIDAZOLE, CLARITHROMYCIN AND LANSOPRAZOLE OF IN TABLETS BY HPLC
Search On Google
